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Publication : Conservation of the human COL1A1-TK-GAA synteny and homoeologous assignment in the African green monkey and the baboon (Cercopithecoidae).

First Author  Créau-Goldberg N Year  1984
Journal  Hum Genet Volume  68
Issue  4 Pages  333-6
PubMed ID  6096258 Mgi Jnum  J:7684
Mgi Id  MGI:56153 Doi  10.1007/BF00292595
Citation  Creau-Goldberg N, et al. (1984) Conservation of the human COL1A1-TK-GAA synteny and homoeologous assignment in the African green monkey and the baboon (Cercopithecoidae). Hum Genet 68(4):333-6
abstractText  The pro alpha 1 (I) collagen structural gene (COL1A1), the acid alpha-glucosidase (GAA), and the thymidine kinase (TK) genes, known to be closely linked in man (HSA) and mapped to HSA17, were found syntenic in two Cercopithecoidae species, the baboon (Papio papio, PPA) and the African green monkey (Cercopithecus aethiops, CAE) and assigned to homoeologous chromosomes, PPA16 and CAE19, respectively. The assignment of COL1A1 was obtained using two human cDNA probes. Hind III restriction sites found in man were present in the two species. The particular CAE individual used in the experiment showed a polymorphism for one DNA fragment.
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