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Publication : Biochemical and immunological characterization of an H2A variant from the mouse testis.

First Author  Bhatnagar YM Year  1985
Journal  Biochim Biophys Acta Volume  827
Issue  1 Pages  14-22
PubMed ID  2578291 Mgi Jnum  J:7706
Mgi Id  MGI:56175 Doi  10.1016/0167-4838(85)90095-0
Citation  Bhatnagar YM, et al. (1985) Biochemical and immunological characterization of an H2A variant from the mouse testis. Biochim Biophys Acta 827(1):14-22
abstractText  A histone H2A variant, protein 'A', has been isolated and purified from the mouse testis. Amino acid composition analysis and electrophoretic properties indicate it to be apparently similar to H2A X X variant present in the mouse L1210 cells. Specific antibodies against protein 'A' have been generated in rabbits and used to study tissue and species distribution in mammals. Protein transfer experiments indicate the presence of antigenically similar proteins in somatic tissues of the mouse. Immunologically similar proteins were also detected in other mammalian testes. The data further indicate that protein A is antigenically distinct from the other members of the H2A family, H2A X 1, H2A X 2 and H2A X Z.
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