First Author | van den Elsen P | Year | 1985 |
Journal | Proc Natl Acad Sci U S A | Volume | 82 |
Issue | 9 | Pages | 2920-4 |
PubMed ID | 3857625 | Mgi Jnum | J:7842 |
Mgi Id | MGI:56311 | Doi | 10.1073/pnas.82.9.2920 |
Citation | van den Elsen P, et al. (1985) Assignment of the gene coding for the T3-delta subunit of the T3-T-cell receptor complex to the long arm of human chromosome 11 and to mouse chromosome 9. Proc Natl Acad Sci U S A 82(9):2920-4 |
abstractText | The gene encoding the 20-kDa glycoprotein of the T3-T-cell receptor complex (T3-delta chain) has been mapped to human chromosome 11 by hybridization of a T3-delta cDNA clone (pPGBC#9) to DNA from a panel of human-rodent somatic cell hybrids. In Southern blotting experiments with DNAs of somatic cell hybrids that contained segments of chromosome 11, we were able to assign the T3-delta gene to the distal portion of the long arm of human chromosome 11 (11q23-11qter). By use of a newly developed cDNA clone (pPEM-T3 delta) that codes for the murine T3-delta chain, the mouse T3-delta gene was mapped on chromosome 9. The importance of the T3-delta map position and its relationship to the other genes on the long arm of human chromosome 11 and to those on mouse chromosome 9 is discussed. |