| First Author | Oliveira OL | Year | 1985 |
| Journal | Immunogenetics | Volume | 21 |
| Issue | 6 | Pages | 559-68 |
| PubMed ID | 2409002 | Mgi Jnum | J:7900 |
| Mgi Id | MGI:56369 | Doi | 10.1007/BF00395880 |
| Citation | Oliveira OL, et al. (1985) A new thymocyte membrane differentiation antigen for mouse and rat. Immunogenetics 21(6):559-68 |
| abstractText | A new thymocyte membrane-brain antigenic system is defined for the mouse and rat. Monoclonal antibody NIM-M129 recognizes a membrane antigen that has a similar size to Thy-1 (20-23 kd) but entirely different tissue distribution. It is absent from cortisone-resistant thymocytes, murine peripheral T cells, T-cell blasts, and T-cell lymphomas, or rat bone marrow. However, the determinant exhibits a quantitative difference in expression on thymocytes of Thy-1a (low) and Thy-1b (high) mice, with intermediate values for their F1 progeny. Backcross and F2 segregation tests between CBA and CBA-Thy-1a congenic lines established firm genetic linkage between Thy-1 and the level of epitope expression on the thymocyte cell surface. |
