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Publication : Chromosomal localization of a human band 3-like gene to region 7q35----7q36.

First Author  Palumbo AP Year  1986
Journal  Am J Hum Genet Volume  39
Issue  3 Pages  307-16
PubMed ID  3020980 Mgi Jnum  J:8444
Mgi Id  MGI:56910 Citation  Palumbo AP, et al. (1986) Chromosomal localization of a human band 3-like gene to region 7q35----7q36. Am J Hum Genet 39(3):307-16
abstractText  Band 3, the major transmembrane protein of erythrocytes, mediates the exchange of anions across the membrane and anchors the erythroid membrane skeleton. Proteins immunologically related to Band 3 have been detected in a variety of nonerythroid cells. We have isolated a human cDNA clone that encodes a protein related to but distinct from the erythroid form of Band 3, based on the comparison of the amino acid sequence for the two proteins. The presence of the gene for the Band 3-like protein in a panel of mouse-human somatic cell hybrids containing subsets of human chromosomes correlated with the presence of human chromosome 7. In situ hybridization analysis using the c-DNA for this nonerythroid Band 3 gene further localized the gene to region 7q35----7q36 of human metaphase chromosomes.
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