| First Author | Birchmeier C | Year | 1986 |
| Journal | Mol Cell Biol | Volume | 6 |
| Issue | 9 | Pages | 3109-16 |
| PubMed ID | 3785223 | Mgi Jnum | J:30975 |
| Mgi Id | MGI:78256 | Doi | 10.1128/mcb.6.9.3109 |
| Citation | Birchmeier C, et al. (1986) Characterization of an activated human ros gene. Mol Cell Biol 6(9):3109-16 |
| abstractText | A human oncogene, mcf3, previously detected by a combination of DNA-mediated gene transfer and a tumorigenicity assay, derives from a human homology of the avian v-ros oncogene. Both v-ros and mcf3 can encode a protein with homology to tyrosine-specific protein kinases, and both mcf3 and v-ros encode a potential transmembrane domain N terminal to the kinase domain. mcf3 probably arose during gene transfer from a normal human ros gene by the loss of a putative extracellular domain. There do not appear to be any other gross rearrangements in the structure of mcf3. |
