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Publication : Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone.

First Author  Mann EA Year  1986
Journal  Genetics Volume  114
Issue  3 Pages  993-1006
PubMed ID  3792827 Mgi Jnum  J:8526
Mgi Id  MGI:56992 Doi  10.1093/genetics/114.3.993
Citation  Mann EA, et al. (1986) Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone. Genetics 114(3):993-1006
abstractText  A mouse kidney cDNA clone, pMK174, identifies restriction fragment length polymorphisms (RFLPs) that map to two unlinked loci. One, designated D17Rp17, has been mapped near quaking, (qk), on chromosome 17 using three sets of recombinant inbred (RI) strains. A study of several t haplotypes resulted in the identification of t-specific alleles of D17Rp17 that map to the proximal half of the t complex. Neither t-specific nor wild-type D17Rp17 alleles are present in chromosomes carrying either the T Orleans (TtOrl) or the T hairpin tail (Thp) deletions. Comparison with other molecular markers indicates that pMK174 identifies a new proximal t complex locus, Rp17. The second locus identified by pMK174, termed D4Rp18, is tentatively assigned to chromosome 4 by mouse-Chinese hamster somatic cell hybrid analysis.
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