| First Author | Naylor SL | Year | 1986 |
| Journal | Am J Hum Genet | Volume | 39 |
| Issue | 6 | Pages | 707-12 |
| PubMed ID | 3026173 | Mgi Jnum | J:8556 |
| Mgi Id | MGI:57022 | Citation | Naylor SL, et al. (1986) Linkage of cystic fibrosis locus and polymorphic DNA markers in 14 families. Am J Hum Genet 39(6):707-12 |
| abstractText | Linkage relationships between the cystic fibrosis (CF) locus and three polymorphic DNA markers were examined in 14 families, five of which were of Hispanic origin. Tight linkage was found between the CF locus and MET (maximum lod score = 7.16 at theta = .001), and between CF and pJ3.11 (maximum lod score = 3.87 at theta = .001). We observed two recombinations between CF and collagen, yielding a maximum lod score of 0.359 at theta = .125, and one recombination in the cluster CF-MET-pJ3.11. Analysis by the seriation method indicates the order COL-pJ3.11-CF-MET. |
