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Publication : Genomic organization of the mouse T-cell receptor beta-chain gene family.

First Author  Lai E Year  1987
Journal  Proc Natl Acad Sci U S A Volume  84
Issue  11 Pages  3846-50
PubMed ID  3035555 Mgi Jnum  J:8736
Mgi Id  MGI:57201 Doi  10.1073/pnas.84.11.3846
Citation  Lai E, et al. (1987) Genomic organization of the mouse T-cell receptor beta-chain gene family. Proc Natl Acad Sci U S A 84(11):3846-50
abstractText  We have combined three different methods, deletion mapping of T-cell lines, field-inversion gel electrophoresis, and the restriction mapping of a cosmid clone, to construct a physical map of the murine T-cell receptor beta-chain gene family. We have mapped 19 variable (V beta) gene segments and the two clusters of diversity (D beta) and joining (J beta) gene segments and constant (C beta) genes. These members of the beta-chain gene family span approximately equal to 450 kilobases of DNA, excluding one potential gap in the DNA fragment alignments.
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