| First Author | Warner CM | Year | 1987 |
| Journal | Biol Reprod | Volume | 36 |
| Issue | 3 | Pages | 606-10 |
| PubMed ID | 3593832 | Mgi Jnum | J:8741 |
| Mgi Id | MGI:57206 | Doi | 10.1095/biolreprod36.3.606 |
| Citation | Warner CM, et al. (1987) Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC). Biol Reprod 36(3):606-10 |
| abstractText | The preimplantation-embryo-development (Ped) gene influences the rate of cleavage division of preimplantation mouse embryos. The location of the Ped gene in the mouse major histocompatibility complex (MHC), the H-2 complex, has been inferred from the analysis of cleavage rates of embryos from mouse strains congenic at the H-2 complex. In this paper, formal genetic linkage studies were undertaken to evaluate linkage of the Ped gene to the H-2 complex. Co-segregation of Ped gene phenotype and H-2 haplotype was found in back-cross embryos. These data support the hypothesis that the Ped gene is linked to the H-2 complex. |
