| First Author | Akao Y | Year | 1987 |
| Journal | Somat Cell Mol Genet | Volume | 13 |
| Issue | 3 | Pages | 273-8 |
| PubMed ID | 2955527 | Mgi Jnum | J:8789 |
| Mgi Id | MGI:57254 | Doi | 10.1007/BF01535209 |
| Citation | Akao Y, et al. (1987) Chromosomal assignments of genes coding for human leukocyte common antigen, T-200, and lymphocyte function-associated antigen 1, LFA-1 beta subunit. Somat Cell Mol Genet 13(3):273-8 |
| abstractText | Five hybrids reactive with monoclonal antibodies against human leukocyte common antigen (T-200) and/or lymphocyte function-associated antigen 1 (LFA-1) beta subunit were obtained from the fusion of human blood lymphocytes or T-cell chronic lymphocytic leukemia cells with BW5147 mouse T-cell leukemia cells. Chromosome analyses of 20 clones showed concordance between the presence of human chromosomes 1 and 21 and the expression of T-200 and LFA-1 beta subunit, respectively. Confirmation of human chromosomes in the hybrids was made by the electrophoretic analyses of phosphoglucomutase for chromosome 1 and superoxide dismutase for chromosome 21. The results suggested that the presence of human chromosomes 1 and 21 was essential for the expression of T-200 and LFA-1 beta subunit, respectively. |
