First Author | Brockdorff N | Year | 1987 |
Journal | EMBO J | Volume | 6 |
Issue | 11 | Pages | 3291-7 |
PubMed ID | 2448136 | Mgi Jnum | J:9005 |
Mgi Id | MGI:57469 | Doi | 10.1002/j.1460-2075.1987.tb02648.x |
Citation | Brockdorff N, et al. (1987) Construction of a detailed molecular map of the mouse X chromosome by microcloning and interspecific crosses. EMBO J 6(11):3291-7 |
abstractText | A large number of microclones obtained by microdissection of the mouse X chromosome have been mapped using an interspecific Mus domesticus/Mus spretus cross. Clones displaying close linkage to a number of loci of known phenotype but unknown gene product, such as mdx (X-linked muscular dystrophy), have been obtained. Over a central 30 cM span of the mouse X chromosome, 17 clones have been mapped and ordered at a sufficient density to contemplate the complete physical mapping of this region that will aid in the isolation of a number of unidentified genes. Some of the mapped microclones detect moderately repetitive sequences that were clustered in several discrete regions of the mouse X chromosome. |