First Author | Ingvarsson S | Year | 1988 |
Journal | Somat Cell Mol Genet | Volume | 14 |
Issue | 4 | Pages | 401-5 |
PubMed ID | 3399964 | Mgi Jnum | J:9274 |
Mgi Id | MGI:57736 | Doi | 10.1007/BF01534648 |
Citation | Ingvarsson S, et al. (1988) Rat c-raf oncogene is located on chromosome 4 and may be activated by sequences from chromosome 13. Somat Cell Mol Genet 14(4):401-5 |
abstractText | Activated forms of the protooncogene c-raf have been found to transform established lines of rodent fibroblasts after transfection with DNA from several human and rat tumors. Using Southern blot analysis of DNAs from rat x mouse somatic cell hybrids, we have mapped c-raf to rat chromosome 4. An exogenous sequence that was found juxtaposed to c-raf within transforming DNA originally derived from a rat hepatocellular carcinoma was localized to chromosome 13. |