First Author | Dahlbäck B | Year | 1988 |
Journal | Somat Cell Mol Genet | Volume | 14 |
Issue | 5 | Pages | 509-14 |
PubMed ID | 3175767 | Mgi Jnum | J:9416 |
Mgi Id | MGI:57877 | Doi | 10.1007/BF01534716 |
Citation | Dahlback B, et al. (1988) Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat. Somat Cell Mol Genet 14(5):509-14 |
abstractText | Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13. |