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Publication : Assignment of retinoblastoma susceptibility gene to mouse chromosome 14.

First Author  Hsieh CL Year  1989
Journal  Somat Cell Mol Genet Volume  15
Issue  5 Pages  461-4
PubMed ID  2781416 Mgi Jnum  J:10018
Mgi Id  MGI:58475 Doi  10.1007/BF01534896
Citation  Hsieh CL, et al. (1989) Assignment of retinoblastoma susceptibility gene to mouse chromosome 14. Somat Cell Mol Genet 15(5):461-4
abstractText  A human cDNA probe was used to screen a panel of mouse-Chinese hamster somatic cell hybrids to determine the chromosomal location of the retinoblastoma susceptibility gene (Rb-1) in mouse. The Rb-1 gene mapped to mouse chromosome 14. Thus, the retinoblastoma susceptibility gene is syntenic with esterase 10 (the mouse homolog of human esterase D). The chromosomal assignment of the mouse Rb-1 gene was further confirmed by using the same probe to study mouse-rat microcell hybrids. Since the human retinoblastoma susceptibility gene (RB1) along with the gene for esterase D is on chromosome 13q14, these data indicate this linkage group is conserved in man and mouse.
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