First Author | Sundaresan S | Year | 1989 |
Journal | Somat Cell Mol Genet | Volume | 15 |
Issue | 5 | Pages | 471-3 |
PubMed ID | 2781418 | Mgi Jnum | J:10020 |
Mgi Id | MGI:58477 | Doi | 10.1007/BF01534898 |
Citation | Sundaresan S, et al. (1989) Gene for alpha 2(I) collagen is on mouse chromosome 6 not 16. Somat Cell Mol Genet 15(5):471-3 |
abstractText | Collagen is the most abundant protein in the animal world and a principal component, of the extracellular matrix of tissues. Type I collagen is composed of two alpha 1 chains and one alpha 2 chain. The human alpha 2(I) locus (COL1A2) has been assigned to human chromosome 7q21.3-q22.1. Here, we report the mapping of its murine counterpart Colla-2 to mouse chromosome 6 (MMU6) by Southern blotting using somatic cell hybrids. This result disagrees with the previously reported mapping of Colla-2 to MMU16 by immunochemical techniques. Our results are supported by comparative mapping data showing conserved homology between regions of human chromosome 7 and mouse chromosome 6. |