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Publication : Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task.

First Author  Ohta A Year  1989
Journal  Brain Res Volume  498
Issue  1 Pages  195-8
PubMed ID  2790474 Mgi Jnum  J:25335
Mgi Id  MGI:73064 Doi  10.1016/0006-8993(89)90421-6
Citation  Ohta A, et al. (1989) Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task. Brain Res 498(1):195-8
abstractText  The behavior of the senescence-accelerated mouse (SAM-P/8) at the age of 1, 2, 4 and 10-11 months in Sidman active avoidance learning was analyzed, and compared to findings in the controls (SAM-R/1). At the age of 1 and 2 months, learning was comparable in these two strains. At the age of 4 and 10-11 months, SAM-P/8 but not SAM-R/1 learned active avoidance. We propose that SAM-P/8 can serve as a valid model of deficits in learning and memory.
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