First Author | Buchberg AM | Year | 1989 |
Journal | Genomics | Volume | 5 |
Issue | 2 | Pages | 363-7 |
PubMed ID | 2676841 | Mgi Jnum | J:10048 |
Mgi Id | MGI:58505 | Doi | 10.1016/0888-7543(89)90071-2 |
Citation | Buchberg AM, et al. (1989) Localization of the murine macrophage colony-stimulating factor gene to chromosome 3 using interspecific backcross analysis. Genomics 5(2):363-7 |
abstractText | The chromosomal location of the murine macrophage colony-stimulating factor (Csfm) gene was determined by interspecific backcross analysis. We mapped Csfm to mouse chromosome 3, 2.5 cM distal to Ngfb and Nras and 1.3 cM proximal to Amy-2. CSFM maps to human chromosome 5q, while AMY2, NGFB, and NRAS map to human chromosome 1p. The chromosomal location of Csfm thus disrupts a previously identified conserved linkage group between mouse chromosome 3 and human chromosome 1. The location of Csfm also identifies yet another mouse chromosome that shares synteny with human chromosome 5q, a region involved in several different types of myeloid disease. |