| First Author | Fet V | Year | 1989 |
| Journal | Genomics | Volume | 5 |
| Issue | 2 | Pages | 375-7 |
| PubMed ID | 2571582 | Mgi Jnum | J:10051 |
| Mgi Id | MGI:58508 | Doi | 10.1016/0888-7543(89)90074-8 |
| Citation | Fet V, et al. (1989) Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance). Genomics 5(2):375-7 |
| abstractText | We have used a cDNA probe for mouse secreted phosphoprotein 1 (Spp-1, also known as 2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphotein, tumor-secreted protein) to find a restriction fragment length polymorphism in the gene from C57BL/6J and DBA/2J mice. The strain distribution pattern in 25 BXD recombinant inbred lines is identical with that previously determined for the dominant, autosomal gene, Ricr (Rickettsia resistance). This places Spp-1 on mouse chromosome 5 with a 95% confidence limit of being within 4.32 cM of Ric. Evidence supporting the possibility of allelism between Spp-1 and Ric is briefly discussed. |
