| First Author | Webb GC | Year | 1990 |
| Journal | Am J Hum Genet | Volume | 46 |
| Issue | 2 | Pages | 308-15 |
| PubMed ID | 2154095 | Mgi Jnum | J:10287 |
| Mgi Id | MGI:58740 | Citation | Webb GC, et al. (1990) Localization of the human UbB polyubiquitin gene to chromosome band 17p11.1-17p12. Am J Hum Genet 46(2):308-15 |
| abstractText | The chromosomal location of the human ubiquitin genes has been evaluated by in situ hybridization. Because of the conservation of the ubiquitin sequence, coding-region probes cannot distinguish between specific ubiquitin genes and reveal ubiquitin sequences in a number of different chromosomal regions. The major sites of hybridization with a coding-region probe include 17p11.1-p12, 12p24.2-q24.32, and 2q21-q24, with weaker hybridization over 1p3, 1q4, 2q3, and 13q. Hybridization with a probe isolated from the UbB gene intron indicated that this gene is located within the region 17p11.1-17p12. This region showed the strongest hybridization with the coding-region probe and is presumably also the location of the duplicated UbB pseudogene. |
