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Publication : Aldehyde dehydrogenase activity in blood from various vertebrates.

First Author  Helander A Year  1989
Journal  Comp Biochem Physiol B Volume  94
Issue  3 Pages  461-4
PubMed ID  2620490 Mgi Jnum  J:26454
Mgi Id  MGI:75436 Doi  10.1016/0305-0491(89)90181-8
Citation  Helander A (1989) Aldehyde dehydrogenase activity in blood from various vertebrates. Comp Biochem Physiol B Biochem Mol Biol 94(3):461-4
abstractText  1. Aldehyde dehydrogenase activity was determined in whole blood samples from 17 selected vertebrates of 5 classes, using 3,4-dihydroxyphenylacetaldehyde (the aldehyde derived from dopamine) as substrate. 2. Aldehyde dehydrogenase activity in blood was widely but unevenly distributed among the species studied. 3. Mean aldehyde dehydrogenase activities in the range of 40-140 nmol/min.ml blood (measured at 37 degrees C, pH 8.8) were found in blood from man, monkey, rabbit, guinea pig and mouse (C57BL and NMRI strains), with the highest activity in rabbit blood. 4. Much lower aldehyde dehydrogenase activities (0.5-7.5 nmol/min.ml blood) were found in blood from Sprague-Dawley and Wistar rat, dog, cat, horse, pig, chicken, caiman, frog and rainbow trout, whereas the activities in blood from DBA mouse, cow, sheep and crucian carp were close to the detection limit.
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