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Publication : Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization.

First Author  Trakhtenbrot L Year  1990
Journal  Leukemia Volume  4
Issue  2 Pages  136-7
PubMed ID  2406516 Mgi Jnum  J:10317
Mgi Id  MGI:58770 Citation  Trakhtenbrot L, et al. (1990) Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization. Leukemia 4(2):136-7
abstractText  Deletion and rearrangement of chromosome 2 were shown to be major cytogenetic characteristics of radiation-induced murine myeloid leukemias. Analysis of the localization of the murine protooncogene c-abl, previously assigned by Goff et al. to chromosome 2, was done using the in situ hybridization method. The c-abl was located close to the centromere, within bands 2A-2B. This site does not correspond to the common characteristic deleted segments (2C-2D) predominantly observed in radiation induced murine myeloid leukemias.
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