First Author | Trakhtenbrot L | Year | 1990 |
Journal | Leukemia | Volume | 4 |
Issue | 2 | Pages | 136-7 |
PubMed ID | 2406516 | Mgi Jnum | J:10317 |
Mgi Id | MGI:58770 | Citation | Trakhtenbrot L, et al. (1990) Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization. Leukemia 4(2):136-7 |
abstractText | Deletion and rearrangement of chromosome 2 were shown to be major cytogenetic characteristics of radiation-induced murine myeloid leukemias. Analysis of the localization of the murine protooncogene c-abl, previously assigned by Goff et al. to chromosome 2, was done using the in situ hybridization method. The c-abl was located close to the centromere, within bands 2A-2B. This site does not correspond to the common characteristic deleted segments (2C-2D) predominantly observed in radiation induced murine myeloid leukemias. |