| First Author | van den Berg EA | Year | 1990 |
| Journal | Genomics | Volume | 7 |
| Issue | 2 | Pages | 276-9 |
| PubMed ID | 2347592 | Mgi Jnum | J:10537 |
| Mgi Id | MGI:58987 | Doi | 10.1016/0888-7543(90)90551-5 |
| Citation | van den Berg EA, et al. (1990) Assignment of the human gene for histidine-rich glycoprotein to chromosome 3. Genomics 7(2):276-9 |
| abstractText | Histidine-rich glycoprotein (HRG) is a monomeric plasma glycoprotein involved in the modulation of coagulation and fibrinolysis. Using Southern analysis of human-rodent somatic cell hybrid DNA with a human HRG-specific cDNA probe, the HRG gene was assigned to chromosome 3. One hybrid that was known to contain only a segment of chromosome 3 also reacted positively with the HRG probe. Hybridization analysis with a set of chromosome 3-specific probes showed that the segment of chromosome 3 present in this hybrid is missing the region pter-p14, which indicates that HRG is not located in this region. No restriction fragment length polymorphisms were detected for HRG with 10 commonly used restriction enzymes. |
