First Author | Keer JT | Year | 1990 |
Journal | Genomics | Volume | 7 |
Issue | 4 | Pages | 566-72 |
PubMed ID | 1974879 | Mgi Jnum | J:10686 |
Mgi Id | MGI:59133 | Doi | 10.1016/0888-7543(90)90200-e |
Citation | Keer JT, et al. (1990) Genetic mapping in the region of the mouse X-inactivation center. Genomics 7(4):566-72 |
abstractText | The mouse X-inactivation center lies just distal to the T16H breakpoint. Utilizing pedigree analysis of backcross progeny from a Mus domesticus/Mus spretus interspecific cross, we have mapped a number of genetic loci, gene probes, microclones, and EagI linking clones distal to the T16H breakpoint. The genetic analysis provides a detailed genetic map in the vicinity of the mouse X-inactivation center. Comparative mapping data from the human X chromosome indicate that the most probable location of the mouse X-inactivation center is distal to Ccg-1 and in the region of the Pgk-1 locus. We report the assignment of two new loci, EM13 and DXSmh44, to the Ccg-1/Pgk-1 interval. |