First Author | Kaye NW | Year | 1990 |
Journal | Somat Cell Mol Genet | Volume | 16 |
Issue | 6 | Pages | 599-603 |
PubMed ID | 2267633 | Mgi Jnum | J:10925 |
Mgi Id | MGI:59368 | Doi | 10.1007/BF01233101 |
Citation | Kaye NW, et al. (1990) Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids. Somat Cell Mol Genet 16(6):599-603 |
abstractText | Laminin is a multichain extracellular matrix glycoprotein found primarily in basement membranes. The molecule is made up of three subunits, designated as A, B1, and B2. Using an 850-base cDNA probe for the mouse laminin A-chain and a 1000-base cDNA probe for the mouse laminin B2 chain, we have screened mouse-Chinese hamster somatic cell hybrids in order to assign the genes for each of these polypeptides to their respective mouse chromosome. We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17. |