| First Author | Kozak CA | Year | 1990 |
| Journal | Genomics | Volume | 8 |
| Issue | 3 | Pages | 519-24 |
| PubMed ID | 1981053 | Mgi Jnum | J:10992 |
| Mgi Id | MGI:59434 | Doi | 10.1016/0888-7543(90)90039-w |
| Citation | Kozak CA, et al. (1990) Molecular genetic markers spanning mouse chromosome 10. Genomics 8(3):519-24 |
| abstractText | Somatic cell hybrids, recombinant inbred (RI) strains, and progeny of an intersubspecific backcross were typed by Southern blot analysis to prepare a linkage map of mouse chromosome 10. The seven genetic markers in this map, four of which had not previously been positioned, include genes involved in oncogenesis (Gli, Myb, Tra-1), proviral integration (Emv-25), and immune responses (Ifg, Ifgr, Pfp). The linkage map spans much of the chromosome and covers a region of the mouse genome with few molecular markers. The gene order established here demonstrates that the genes for murine interferon-gamma (Ifg) and its receptor (Ifgr) are at opposite ends of the chromosome and that Ifgr and the Myb oncogene are closely linked, a factor that may be related to their joint transcriptional enhancement in some plasmacytoid lymphosarcomas. |
