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Publication : Genetic mapping of the gene for Ca2+/calmodulin-dependent protein kinase IV (Camk-4) to mouse chromosome 18.

First Author  Sikela JM Year  1990
Journal  Genomics Volume  8
Issue  3 Pages  579-82
PubMed ID  1981056 Mgi Jnum  J:10997
Mgi Id  MGI:59439 Doi  10.1016/0888-7543(90)90048-y
Citation  Sikela JM, et al. (1990) Genetic mapping of the gene for Ca2+/calmodulin-dependent protein kinase IV (Camk-4) to mouse chromosome 18. Genomics 8(3):579-82
abstractText  Southern blot analysis of Chinese hamster x mouse somatic cell hybrids was used to map the gene for a serine/threonine protein kinase expressed in brain and testis. This locus, termed Camk-4, encodes Ca2+/calmodulin-dependent protein kinase IV. Progeny of an interspecific backcross were analyzed to position Camk-4 in the centromeric region of chromosome 18 near two mutations known to affect neurological function and fertility. This raises the possibility that a defect in Camk-4 may be responsible for one of these mutant phenotypes.
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