| First Author | Elliott RW | Year | 1990 |
| Journal | Genomics | Volume | 8 |
| Issue | 3 | Pages | 591-4 |
| PubMed ID | 2286379 | Mgi Jnum | J:10999 |
| Mgi Id | MGI:59441 | Doi | 10.1016/0888-7543(90)90051-u |
| Citation | Elliott RW, et al. (1990) Localization of the growth hormone gene to the distal half of mouse chromosome 11. Genomics 8(3):591-4 |
| abstractText | A DNA fragment size variant for the growth hormone gene, Gh, has been identified among inbred strains of mice. The inbred strains SM/J and CAST/Ei carry the less frequent allele Ghb and 11 other strains carry the Gha allele. Segregation analysis of data from two crosses involving SM/J and NZB/BINJ and a cross involving BALB/cJ and CAST/Ei confirmed the assignment of Gh to mouse chromosome 11 and placed the locus 2.6 +/- 1.8 map units distal to Erba (avian erythroblastosis oncogene A), a position consistent with the assignment of the Gh locus to the q22-q24 region of chromosome 17 on the human map. Segregation analysis also refined the location of Sparc (secreted acidic cysteine-rich glycoprotein) on mouse chromosome 11 to a position 16.7 +/- 4.2 map units proximal to Evi-2 (ecotropic viral integration site 2). |
