| First Author | Yachou A | Year | 1991 |
| Journal | Genomics | Volume | 9 |
| Issue | 1 | Pages | 204-6 |
| PubMed ID | 2004762 | Mgi Jnum | J:11041 |
| Mgi Id | MGI:59483 | Doi | 10.1016/0888-7543(91)90240-f |
| Citation | Yachou A, et al. (1991) Mouse ferritin H sequences map to chromosomes 3, 6, and 19. Genomics 9(1):204-6 |
| abstractText | Human and rodent genomes contain multiple copies of ferritin H and L subunit sequences, although it is not yet clear whether there is more than one expressed gene for either of these subunits. We have isolated a cDNA corresponding to mouse ferritin H subunit and observed that the mouse genome contains three to four H-related sequences. This cDNA was used to establish the genomic location of mouse ferritin H subunit genes by chromosomal in situ hybridization. Metaphase chromosomes of concanavalin A-stimulated lymphocytes from a WMP male mouse were examined by in situ hybridization with 3H-labeled cDNA and the chromosomes were identified by R banding (fluorochrome-photolysis-Giemsa method). The results indicate that mouse ferritin H-related sequences map at chromosomes 3, 6, and 19. Homology of synteny between human and mouse suggests that the sequence on mouse chromosome 19 corresponds to the structural H gene. |
