First Author | Chainani M | Year | 1991 |
Journal | Genomics | Volume | 9 |
Issue | 2 | Pages | 376-9 |
PubMed ID | 2004789 | Mgi Jnum | J:11060 |
Mgi Id | MGI:59502 | Doi | 10.1016/0888-7543(91)90269-k |
Citation | Chainani M, et al. (1991) Localization of the gene for plasma retinol binding protein to the distal half of mouse chromosome 19. Genomics 9(2):376-9 |
abstractText | A DNA polymorphism for the mouse retinol binding protein has been identified using the enzyme BamHI and a rat partial cDNA probe. Analysis of the polymorphism in DNA from 64 inbred mouse strains demonstrated the presence of a single gene with two alleles, Rbp-4b and Rbp-4d. Comparison of the segregation patterns of these alleles in three sets of recombinant inbred strains with allele segregation patterns of previously characterized loci shows that the Rbp-4 locus is closely linked to the locus for phenobarbital-inducible cytochrome P450-2c (Cyp-2c) that has been shown by in situ hybridization to lie on chromosome 19, bands D1-D2. The Rbp-4 locus is just proximal to Cyp-2c at the distal end of chromosome 19. |