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Publication : Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping.

First Author  Welsh J Year  1991
Journal  Nucleic Acids Res Volume  19
Issue  2 Pages  303-6
PubMed ID  2014169 Mgi Jnum  J:17666
Mgi Id  MGI:65697 Doi  10.1093/nar/19.2.303
Citation  Welsh J, et al. (1991) Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping. Nucleic Acids Res 19(2):303-6
abstractText  Polymorphisms in genomic fingerprints generated by arbitrarily primed PCR (AP-PCR) can distinguish between strains of almost any organism. We applied the technique to the mouse (Mus musculus). The characteristic differences in the AP-PCR genomic fingerprints between strains will be of value in strain identification and verification. Using one primer, we genetically mapped four polymorphisms in a set of C57BL/6J x DBA/2J recombinant inbreds. One of these polymorphisms is a length variant. The method will allow rapid genetic mapping of DNA polymorphisms without Southern blotting.
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