First Author | Welsh J | Year | 1991 |
Journal | Nucleic Acids Res | Volume | 19 |
Issue | 2 | Pages | 303-6 |
PubMed ID | 2014169 | Mgi Jnum | J:17666 |
Mgi Id | MGI:65697 | Doi | 10.1093/nar/19.2.303 |
Citation | Welsh J, et al. (1991) Polymorphisms generated by arbitrarily primed PCR in the mouse: application to strain identification and genetic mapping. Nucleic Acids Res 19(2):303-6 |
abstractText | Polymorphisms in genomic fingerprints generated by arbitrarily primed PCR (AP-PCR) can distinguish between strains of almost any organism. We applied the technique to the mouse (Mus musculus). The characteristic differences in the AP-PCR genomic fingerprints between strains will be of value in strain identification and verification. Using one primer, we genetically mapped four polymorphisms in a set of C57BL/6J x DBA/2J recombinant inbreds. One of these polymorphisms is a length variant. The method will allow rapid genetic mapping of DNA polymorphisms without Southern blotting. |