First Author | von Deimling OH | Year | 1991 |
Journal | Genet Res | Volume | 57 |
Issue | 1 | Pages | 61-70 |
PubMed ID | 2040456 | Mgi Jnum | J:11217 |
Mgi Id | MGI:59658 | Doi | 10.1017/s0016672300029050 |
Citation | von Deimling OH, et al. (1991) Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus). Genet Res 57(1):61-70 |
abstractText | Esterase-27A (ES-27A) was characterized in strain A/WySnA by a cascade of seven bands seen after disc electrophoresis of serum and subsequent staining for esterase. ES-27A catalyses the hydrolysis of thiocholine butyrate and is strongly inhibited by 100 microM tetraisopropyl pyrophosphamide (isoOMPA). Hence, the enzyme was concluded to be a cholinesterase EC 3.1.1.8. A heat-labile form termed ES-27B was represented by strain AKR/Han. From a three-point cross (AKR/Han, A/Wy) and a five-point cross (AKR/Han, SEG/1), the gene order on chromosome 3 was concluded to be centromere-Car-2-Es-26-Es-27-Amy-1-Adh-1. |