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Publication : Mapping HSA10 homologous loci in cattle.

First Author  Threadgill DS Year  1991
Journal  Cytogenet Cell Genet Volume  57
Issue  2-3 Pages  123-6
PubMed ID  1655359 Mgi Jnum  J:15066
Mgi Id  MGI:63209 Doi  10.1159/000133130
Citation  Threadgill DS, et al. (1991) Mapping HSA10 homologous loci in cattle. Cytogenet Cell Genet 57(2-3):123-6
abstractText  Loci homologous to those on human chromosome 10 (HSA10) map to five mouse chromosomes, MMU2, MMU7, MMU10, MMU14, and MMU19. In cattle, one unassigned syntenic group (U26) was previously defined by the HSA10/MMU19 isoenzyme marker glutamic-oxaloacetic transaminase 1 (GOT1). To evaluate the syntenic arrangement of other HSA10 loci in cattle, seven genes were physically mapped by segregation analysis in a bovine x hamster hybrid somatic cell panel. The genes mapped include: vimentin (VIM) on HSA10 and MMU2; interleukin 2 receptor (IL2R) on HSA10 and MMU?; ornithine aminotransferase (OAT) on HSA10 and MMU7; hexokinase 1 (HK1) on HSA10 and MMU10; retinol-binding protein 3 (RBP3) on HSA10 and MMU14; plasminogen activator, urokinase type (PLAU) on HSA10 and MMU14; and alpha-2-adrenergic receptor (ADRA2) on HSA10 and MMU19. VIM and IL2R mapped to U11; ADRA2 and OAT mapped to U26; and RBP3, PLAU, and HK1 mapped to U28.
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