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Publication : Co-segregation of a gene encoding a deletion ligand for Tcrb-V3+ T cells with Mtv-3.

First Author  Fairchild S Year  1991
Journal  Immunogenetics Volume  34
Issue  4 Pages  227-30
PubMed ID  1655644 Mgi Jnum  J:11490
Mgi Id  MGI:59923 Doi  10.1007/BF00215257
Citation  Fairchild S, et al. (1991) Co-segregation of a gene encoding a deletion ligand for Tcrb-V3+ T cells with Mtv-3. Immunogenetics 34(4):227-30
abstractText  A gene encoding the endogenous superantigen Mlsc, which deletes Tcrb-V3+ T cells in the NOD inbred mouse strain, was found to co-segregate with Mtv-3 on chromosome 11. This identifies a fourth gene encoding a deletion ligand for Tcrb-V3+ T cells and extends recently published observations in support of the hypothesis that a number of endogenous superantigens are the products of Mtv proviruses.
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