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Publication : Localization of the amphotropic murine leukemia virus receptor gene to the pericentromeric region of human chromosome 8.

First Author  Garcia JV Year  1991
Journal  J Virol Volume  65
Issue  11 Pages  6316-9
PubMed ID  1656098 Mgi Jnum  J:539
Mgi Id  MGI:49076 Doi  10.1128/jvi.65.11.6316-6319.1991
Citation  Garcia JV, et al. (1991) Localization of the amphotropic murine leukemia virus receptor gene to the pericentromeric region of human chromosome 8. J Virol 65(11):6316-9
abstractText  The host range of retroviruses is determined primarily by the presence of specific receptors on target cells which are recognized by the retroviral envelope glycoprotein. Somatic cell hybrids have been used to determine the chromosomal locations of several retroviral receptors in mice prior to their molecular cloning. Here we report that by using human-Chinese hamster somatic cell hybrids and a retroviral vector, we have mapped the receptor for the amphotropic murine leukemia virus to the pericentromeric region of human chromosome 8.
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