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Publication : The human homolog of the mouse brown gene maps to the short arm of chromosome 9 and extends the known region of homology with mouse chromosome 4.

First Author  Abbott C Year  1991
Journal  Genomics Volume  11
Issue  2 Pages  471-3
PubMed ID  1769662 Mgi Jnum  J:446
Mgi Id  MGI:48983 Doi  10.1016/0888-7543(91)90160-g
Citation  Abbott C, et al. (1991) The human homolog of the mouse brown gene maps to the short arm of chromosome 9 and extends the known region of homology with mouse chromosome 4. Genomics 11(2):471-3
abstractText  The mouse brown locus encodes a tyrosinase-related protein, TRP-1. The human homolog of TRP-1 was recently cloned from a melanoma cDNA library and sequenced. We have made oligonucleotide primers corresponding to the human TRP1 3' untranslated region and used them to map the human TRP1 gene by species-specific PCR in human/rodent somatic cell hybrids. By this means, the human TRP1 gene has been mapped to the short arm of chromosome 9.
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