First Author | Zamore PD | Year | 1992 |
Journal | Nature | Volume | 355 |
Issue | 6361 | Pages | 609-14 |
PubMed ID | 1538748 | Mgi Jnum | J:24046 |
Mgi Id | MGI:71835 | Doi | 10.1038/355609a0 |
Citation | Zamore PD, et al. (1992) Cloning and domain structure of the mammalian splicing factor U2AF. Nature 355(6361):609-14 |
abstractText | A complementary DNA clone encoding the large subunit of the essential mammalian pre-messenger RNA splicing component U2 snRNP auxiliary factor (U2AF65) has been isolated and expressed in vitro. It contains two functional domains: a sequence-specific RNA-binding region composed of three ribonucleoprotein-consensus sequence domains, and an arginine/serine-rich motif necessary for splicing but not for binding to pre-mRNA. |