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Publication : Cloning and domain structure of the mammalian splicing factor U2AF.

First Author  Zamore PD Year  1992
Journal  Nature Volume  355
Issue  6361 Pages  609-14
PubMed ID  1538748 Mgi Jnum  J:24046
Mgi Id  MGI:71835 Doi  10.1038/355609a0
Citation  Zamore PD, et al. (1992) Cloning and domain structure of the mammalian splicing factor U2AF. Nature 355(6361):609-14
abstractText  A complementary DNA clone encoding the large subunit of the essential mammalian pre-messenger RNA splicing component U2 snRNP auxiliary factor (U2AF65) has been isolated and expressed in vitro. It contains two functional domains: a sequence-specific RNA-binding region composed of three ribonucleoprotein-consensus sequence domains, and an arginine/serine-rich motif necessary for splicing but not for binding to pre-mRNA.
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