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Publication : MyoD and myogenin are coexpressed in regenerating skeletal muscle of the mouse.

First Author  Füchtbauer EM Year  1992
Journal  Dev Dyn Volume  193
Issue  1 Pages  34-9
PubMed ID  1311614 Mgi Jnum  J:1900
Mgi Id  MGI:50424 Doi  10.1002/aja.1001930106
Citation  Fuchtbauer EM, et al. (1992) MyoD and myogenin are coexpressed in regenerating skeletal muscle of the mouse. Dev Dyn 193(1):34-9
abstractText  The differential expression of genes triggering myogenesis might cause or reflect differences among myoblasts. Little is known about the presence of MyoD1 and myogenin during the process of regeneration. We therefore examined the expression of MyoD1 and myogenin in muscle regeneration after grafting. Immunostaining of regenerating skeletal muscle of the mouse revealed the presence of both MyoD1 and myogenin. In mononucleated cells the proteins were not detected until shortly before fusion into myotubes. They persisted in the nuclei of regenerated muscle fibers for at least 2 weeks. MyoD1 and myogenin were not detected in nonregenerating control muscle.
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