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Publication : Localization of the calcium release channel gene in cattle and horse by in situ hybridization: evidence of a conserved synteny with glucose phosphate isomerase.

First Author  Chowdhary BP Year  1992
Journal  Anim Genet Volume  23
Issue  1 Pages  43-50
PubMed ID  1315127 Mgi Jnum  J:351
Mgi Id  MGI:48889 Citation  Chowdhary BP, et al. (1992) Localization of the calcium release channel gene in cattle and horse by in situ hybridization: evidence of a conserved synteny with glucose phosphate isomerase. Anim Genet 23(1):43-50
abstractText  In situ hybridization techniques were used to localize regionally the calcium release channel (CRC) gene on cattle and horse chromosomes, using a porcine CRC cDNA probe. In cattle, the hybridization signal peaked on the 18q23-q26 bands and in horse on the 10pter region. Previous studies have shown that the glucose phosphate isomerase (GPI) gene localizes at the same site in both species, indicating that the two loci are syntenic. As CRC and GPI are syntenic in human, pig and mouse, the present results in cattle and horse represent another example of synteny conservation in the evolution of mammalian chromosomes.
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