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Publication : Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development.

First Author  Dollé P Year  1992
Journal  Differentiation Volume  49
Issue  2 Pages  93-9
PubMed ID  1350766 Mgi Jnum  J:586
Mgi Id  MGI:49123 Doi  10.1111/j.1432-0436.1992.tb00773.x
Citation  Dolle P, et al. (1992) Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development. Differentiation 49(2):93-9
abstractText  We have analysed the expression pattern of the mouse homeobox containing gene Dlx-1. This gene harbors a homeodomain related to that found in the Drosophila distal-less (dll) gene. In addition to its expression in the developing forebrain, Dlx-1 is transcribed in several structures containing cells of neural crest origin such as the facial mesenchyme and various elements of the peripheral nervous system. Dlx-1 transcripts are also detected in the differentiating retina and during limb morphogenesis, in the apical ectodermal ridge. The possible involvement of Dlx-1 during facial, ocular and limb development is discussed.
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