First Author | Dollé P | Year | 1992 |
Journal | Differentiation | Volume | 49 |
Issue | 2 | Pages | 93-9 |
PubMed ID | 1350766 | Mgi Jnum | J:586 |
Mgi Id | MGI:49123 | Doi | 10.1111/j.1432-0436.1992.tb00773.x |
Citation | Dolle P, et al. (1992) Expression of the murine Dlx-1 homeobox gene during facial, ocular and limb development. Differentiation 49(2):93-9 |
abstractText | We have analysed the expression pattern of the mouse homeobox containing gene Dlx-1. This gene harbors a homeodomain related to that found in the Drosophila distal-less (dll) gene. In addition to its expression in the developing forebrain, Dlx-1 is transcribed in several structures containing cells of neural crest origin such as the facial mesenchyme and various elements of the peripheral nervous system. Dlx-1 transcripts are also detected in the differentiating retina and during limb morphogenesis, in the apical ectodermal ridge. The possible involvement of Dlx-1 during facial, ocular and limb development is discussed. |