First Author | Varesco L | Year | 1992 |
Journal | Genes Chromosomes Cancer | Volume | 4 |
Issue | 1 | Pages | 84-8 |
PubMed ID | 1377015 | Mgi Jnum | J:435 |
Mgi Id | MGI:48972 | Doi | 10.1002/gcc.2870040113 |
Citation | Varesco L, et al. (1992) The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII. Genes Chromosomes Cancer 4(1):84-8 |
abstractText | The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process. Recent genetic and immunological data indicate that the NM23-Hl gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-Hl by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele polymorphism with BglII was demonstrated. |