First Author | Hart CP | Year | 1992 |
Journal | J Exp Zool | Volume | 263 |
Issue | 1 | Pages | 83-95 |
PubMed ID | 1379621 | Mgi Jnum | J:1561 |
Mgi Id | MGI:50088 | Doi | 10.1002/jez.1402630109 |
Citation | Hart CP, et al. (1992) Genetic linkage analysis of the murine developmental mutant velvet coat (Ve) and the distal chromosome 15 developmental genes Hox-3.1, Rar-g, Wnt-1, and Krt-2. J Exp Zool 263(1):83-95 |
abstractText | We have identified restriction fragment length polymorphisms between Mus musculus and Mus spretus for the Chromosome 15 loci Hox-3, Wnt-1, Krt-2, Rar-g, and Ly-6. We followed the inheritance of these alleles in interspecific genetic test crosses between velvet coat (Ve) heterozygotes and M. spretus. The results suggest a gene order and recombination distances (in cM) of Ly-6-22-Wnt-1-2-Ve/Krt-2/Rar-g-3-Hox-3. No recombination was found between Ve, Krt-2, and Rar-g. The data also provide evidence for the hypothesis of a large-scale genomic duplication involving homologous gene pairs on mouse Chromosomes 15 and 11. |