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Publication : Regulation of transferrin gene expression.

First Author  Zakin MM Year  1992
Journal  FASEB J Volume  6
Issue  14 Pages  3253-8
PubMed ID  1426763 Mgi Jnum  J:3217
Mgi Id  MGI:51732 Doi  10.1096/fasebj.6.14.1426763
Citation  Zakin MM (1992) Regulation of transferrin gene expression. FASEB J 6(14):3253-8
abstractText  Transferrin (Tf) is the iron-transport protein of vertebrate serum. It is essentially synthesized in the liver, but lower amounts are also produced in other organs, such as testis and brain. A number of studies have been done to characterize the transcriptional elements implicated in the regulation of Tf gene expression in different organs. The results of these studies support the hypothesis that the Tf gene makes use of different combinations of nuclear proteins in different subsets of cells to achieve tissue-specific expression. It is interesting to point out that this occurs in tissues arising from different embryological origin.
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