| First Author | de Giorgi L | Year | 1992 |
| Journal | Immunol Lett | Volume | 33 |
| Issue | 3 | Pages | 295-300 |
| PubMed ID | 1428006 | Mgi Jnum | J:2556 |
| Mgi Id | MGI:51078 | Doi | 10.1016/0165-2478(92)90076-z |
| Citation | de Giorgi L, et al. (1992) Anti-TCR-V beta 6 breaks tolerance in female AKR, Mlsa mice inducing foetal lethality. Immunol Lett 33(3):295-300 |
| abstractText | Immunisation with anti-TCR-V beta 6 of female AKR mice prior to and during syngeneic pregnancy resulted in neonatal lethality and eventually in abortion or foetal resorption. The sera of the hyperimmunised mothers were shown to have anti-H-2k and anti-Mlsa autoantibodies and were cytotoxic to H-2k targets in vitro and also blocked Mlsa-induced mixed lymphocyte reactions. These observations are discussed herein. |
