| First Author | Levy HP | Year | 1992 |
| Journal | Cytogenet Cell Genet | Volume | 61 |
| Issue | 4 | Pages | 276-81 |
| PubMed ID | 1486805 | Mgi Jnum | J:3587 |
| Mgi Id | MGI:52099 | Doi | 10.1159/000133422 |
| Citation | Levy HP, et al. (1992) Comparative gene mapping in the species Muntiacus muntjac. Cytogenet Cell Genet 61(4):276-81 |
| abstractText | An extreme case of chromosomal evolution is presented by the two muntjac species Muntiacus muntjac (Indian muntjac, 2n = 6 [females], 7 [males]) and M. reevesi (Chinese muntjac, 2n = 46). Despite disparate karyotypes, these phenotypically similar species produce viable hybrid offspring, indicating a high degree of DNA-level conservation and genetic relatedness. As a first step toward development of a comparative gene map, several Indian muntjac homologs of known human type I anchor loci were mapped. Using flow-sorted, chromosome-specific Southern hybridization techniques, homologs of the protein kinase C beta polypeptide (PRKCB1) and the DNA repair genes ERCC2 and XRCC1 have been assigned to Indian muntjac chromosome 2. The male-specific ZFY gene was presumptively mapped to Indian muntjac chromosome Y2. Ultimate generation of a comparative physical map of both Indian and Chinese muntjac chromosomes will prove invaluable in the study of mammalian karyotype evolution. |
