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Publication : Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.

First Author  Luongo C Year  1993
Journal  Genomics Volume  15
Issue  1 Pages  3-8
PubMed ID  8094372 Mgi Jnum  J:3803
Mgi Id  MGI:52311 Doi  10.1006/geno.1993.1002
Citation  Luongo C, et al. (1993) Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. Genomics 15(1):3-8
abstractText  The Min (multiple intestinal neoplasia) mutation of the mouse has been mapped by analyzing the inheritance of restriction fragment length polymorphisms and simple sequence length polymorphisms in progeny from two intraspecific crosses segregating for the Min mutation. Min, a mutant allele of Apc, the mouse homolog of the human APC (adenomatous polyposis coli) gene, maps to proximal chromosome 18. The synteny between Apc and Mcc, the mouse homolog of the human MCC (mutated in colorectal cancer) gene, is conserved between mouse and human, although the gene order in the Apc to Mcc interval is different from that in the APC to MCC interval.
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