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Publication : The human pseudoautosomal GM-CSF receptor alpha subunit gene is autosomal in mouse.

First Author  Disteche CM Year  1992
Journal  Nat Genet Volume  1
Issue  5 Pages  333-6
PubMed ID  1363815 Mgi Jnum  J:1831
Mgi Id  MGI:50355 Doi  10.1038/ng0892-333
Citation  Disteche CM, et al. (1992) The human pseudoautosomal GM-CSF receptor alpha subunit gene is autosomal in mouse. Nat Genet 1(5):333-6
abstractText  The gene encoding the granulocyte macrophage colony stimulating factor receptor alpha subunit (CSF2RA) has previously been mapped to the pseudoautosomal region of the human sex chromosomes. In contrast, we report that the murine locus, Csf2ra, maps to an autosome in the laboratory mouse. By in situ hybridization and genetic mapping, Csf2ra maps at telomeric band D2 of mouse chromosome 19. This first instance of a pseudoautosomal locus in human being autosomal in mouse, indicates incomplete conservation between the human and mouse X chromosomes and suggests that the genetic content of the pseudoautosomal region may differ between species of eutherian mammals due to chromosomal rearrangements.
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