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Publication : The human C/EBP delta (CRP3/CELF) gene: structure and chromosomal localization.

First Author  Cleutjens CB Year  1993
Journal  Genomics Volume  16
Issue  2 Pages  520-3
PubMed ID  8314590 Mgi Jnum  J:4945
Mgi Id  MGI:53424 Doi  10.1006/geno.1993.1220
Citation  Cleutjens CB, et al. (1993) The human C/EBP delta (CRP3/CELF) gene: structure and chromosomal localization. Genomics 16(2):520-3
abstractText  In an attempt to identify C/EBP-like transcription factors expressed in the prostate, a cDNA homologous to the mouse C/EBP delta (CRP3) and the rat CELF gene was isolated. A genomic clone containing the entire C/EBP delta gene was isolated using a cDNA fragment as a probe. The gene was characterized by restriction mapping and sequence analysis. By fluorescence in situ hybridization, using the biotinylated genomic clone as a probe, the C/EBP delta gene was assigned to the pericentromeric region of human chromosome 8, most probably to 8q11. This chromosomal localization was confirmed by analysis of a panel of human x hamster somatic cell hybrid DNA samples with a C/EBP delta-specific STS. As a result, the C/EBP delta gene could be positioned between the PLAT and the MOS loci.
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