First Author | Cleutjens CB | Year | 1993 |
Journal | Genomics | Volume | 16 |
Issue | 2 | Pages | 520-3 |
PubMed ID | 8314590 | Mgi Jnum | J:4945 |
Mgi Id | MGI:53424 | Doi | 10.1006/geno.1993.1220 |
Citation | Cleutjens CB, et al. (1993) The human C/EBP delta (CRP3/CELF) gene: structure and chromosomal localization. Genomics 16(2):520-3 |
abstractText | In an attempt to identify C/EBP-like transcription factors expressed in the prostate, a cDNA homologous to the mouse C/EBP delta (CRP3) and the rat CELF gene was isolated. A genomic clone containing the entire C/EBP delta gene was isolated using a cDNA fragment as a probe. The gene was characterized by restriction mapping and sequence analysis. By fluorescence in situ hybridization, using the biotinylated genomic clone as a probe, the C/EBP delta gene was assigned to the pericentromeric region of human chromosome 8, most probably to 8q11. This chromosomal localization was confirmed by analysis of a panel of human x hamster somatic cell hybrid DNA samples with a C/EBP delta-specific STS. As a result, the C/EBP delta gene could be positioned between the PLAT and the MOS loci. |