| First Author | Nass SJ | Year | 1993 |
| Journal | Mamm Genome | Volume | 4 |
| Issue | 6 | Pages | 333-7 |
| PubMed ID | 8100460 | Mgi Jnum | J:12629 |
| Mgi Id | MGI:60867 | Doi | 10.1007/BF00357093 |
| Citation | Nass SJ, et al. (1993) Mapping of the Mod-1 locus on mouse chromosome 9. Mamm Genome 4(6):333-7 |
| abstractText | A new method for typing the Mod-1 locus on mouse Chromosome (Chr) 9 was developed, based on restriction fragment length polymorphism (RFLP) within a polymerase chain reaction (PCR)-amplified fragment. The new method led us to revise the strain distribution pattern (SDP) of Mod-1 in the BXD (C57BL/6J x DBA/2J) and AKXD (AKR/J x DBA/2J) recombinant inbred (RI) strains. The new SDP eliminates several previously reported examples of double recombination events between Mod-1 and the closest flanking loci in the BXD and AKXD strains. In the BXD strains, the revised SDP of Mod-1 was identical to that of the Mod-1-related D9Rtil locus. Thus, the identity of D9Rtil as a Mod-1-related locus rather than Mod-1 itself is in question. The method was also applied to an interspecific backcross panel between an inbred strain of Mus musculus molossinus (MSM/Ms) and C57BL/6J to map Mod-1 with respect to surrounding microsatellite loci, defining the proximal localization of Mod-1 with respect to D9Mit10 with a genetic distance of 0.6 +/- 0.6 cM. |
