| First Author | Mjaatvedt AE | Year | 1993 |
| Journal | Genomics | Volume | 17 |
| Issue | 2 | Pages | 382-6 |
| PubMed ID | 8406490 | Mgi Jnum | J:13578 |
| Mgi Id | MGI:61764 | Doi | 10.1006/geno.1993.1336 |
| Citation | Mjaatvedt AE, et al. (1993) High-resolution mapping of D16led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16. Genomics 17(2):382-6 |
| abstractText | More than 500 backcross progeny from four intersubspecific backcrosses were typed for six markers on distal mouse chromosome 16. Five of these represented genes that mapped within the Sod-1 to Ets-2 interval, which was shown previously to contain the weaver (wv) gene. The map order, including previously mapped reference markers, is (cen)-D16H21S16-D16Led-1-App-Sod-1-Gart-Gas-4-Cbr++ +-wv-Pcp-4-Erg-Ets-2. This gene order recapitulates the order of the genes on human chromosome 21 where known. Two of these markers further define the region containing the weaver gene to a 3.9-cM segment between Cbr and Pcp-4. In addition, Pcp-4 was localized to human chromosome 21 by the presence of a human-specific restriction fragment in WAV-17, a mouse-human somatic cell hybrid with human chromosome 21 as the only human contribution. |
